FluidFM® BOT BIO Series



For single cell research & nanoprinting.
Cutting-edge & easy to use.

The FluidFM BOT BIO Series enables single cell experiments - from single cell gene editing to drug research and toxicology on a single cell level. Beyond that the BIO Series can also print structures from sub-micrometer to millimeter in scale - for sensing applications, mechanobiology and more. Explore the applications.

The system is highly automated, easy to use and features a fully enclosing incubator. Benefit from simple preparation as well as extensive automation and observation features. 

Download the system brochure

CRISPR-Cas complexes direct delivery - Straight-forward multiplex & stack editing

Easy to set up. Easy to use.

Ready in 10 minutes

Simple & fast system preparation.

Fast learning curve

Intuitive operator software.

Save precious material

The FluidFM probe is filled with less than 1 µl solution. Zero dead volume.

Probe exchange in 5 minutes

Automatic probe gripping.

No prior technical expertise needed

Point-and-click cell selection. Easily adjustable parameters.

Fits cell-lab workflow

Compatible with most cell-culture well plates.

Benefit from versatile applications

Enabled by the FluidFM core methods:

Odoo - Sample 1 for three columns

    Volumetric injection & sampling

Injection into and extraction from single cells. With the possibility to quantify the injected or extracted volume.

Odoo - Sample 2 for three columns

    Pick & place

Grab and relocate single cells and other micro-sized objects. Automatize single cell adhesion assays.

Odoo - Sample 3 for three columns

    Localized dispensing

Dispense the tiniest amount of liquid. In air or in immersion.

Point and click interface

  • Application-specific workflows

  • Easy cell selection - target the nucleus or cytoplasm

  • XY-coordinates of the edited cells are being recorded

  • Observation and time lapse features

  • Multi-user data management

Stand-alone system

  • Temperature and CO2-controlled incubator

  • Fluorescence microscopy – up to 8 filter sets

  • Fully motorized

  • Minimal footprint

  • Powered by an Olympus IX83 microscope

  • Fully compatible with standard cell culture containers from petri-dishes to 12 & 24 well plates

CRISPR-Cas complexes direct delivery - Straight-forward multiplex & stack editing

         FluidFM BOT BIO Series - system outline with incubator.

FluidFM probes

The patented hollow FluidFM probes are the core of the technology when performing FluidFM applications. The consumables are available in a broad variety of tip shapes, aperture sizes and mechanical specifications.

Learn more about our FluidFM probes


Demo Logo
Demo Logo
Demo Logo
Demo Logo
Demo Logo
Demo Logo

Preserve cellular environment

Perform any experiment on adherent cell cultures and keep the valuable context information. A unique advantage of FluidFM technology.

>95% viability

For any single cell manipulation. Higher viability than any other single cell technique.

70+ Publications

Since its invention in 2009, FluidFM facilitates cutting-edge research results in life sciences, biophysics and mechanobiology. Explore the 70+ publications.