Writing and spotting at the micro- and nanoscale. 

With any ink. In liquid & air.


From µm to cm - any pattern with sub-micrometer resolution

Our long-range XY-stage enables precise printing of 2.5D patterns at any size from µm to cm.

Print spots from micro- to nanoscale, choosing the appropriate FluidFM probe type ( apertures ranging from 300 nm to 8 µm).

Millimeter-sized patterns with micrometer resolution for cell patterning:
A. Saftics et al. Biomimetic dextran-based hydrogel layers for cell micropatterning over large areas using the FluidFM BOT technology. Langmuir, 2019.

Fine patterns with nanometer resolution:
J.V. de Souza et al. Three-Dimensional Nanoprinting via Direct Delivery. The Journal Of Physical Chemistry B, 2017.

Choose the most adequate nozzle geometry and size

   FluidFM nanopipette

  • - Direct ink-substrate contact

  • - Sub-micrometer lines
    - For high-resolution patterns
  • In liquid & air

   FluidFM nanosyringe

  • - Controlled tip-substrate contact

  • - Sub-micrometer lines
    - For high-resolution patterns
  • In air

   FluidFM micropipette

  • - Higher deposition rate
    - 2, 4 and 8 µm diameter choice
  • - Ideal for spotting
    - For high material deposition rate
  • In liquid & air

With any ink

Any liquid with viscosities ranging from 1 cP to 10'000 cP (water to honey) can be pipetted into the 1 µl reservoir and dispensed through our FluidFM probes.

Use virtually any soluble substance: DNA, RNA, proteins, nanoparticle solutions and many other.

Discuss your experiment with our experts

A close view of the FluidFM probe consumable, integrating reservoir and micro- or nano- meter sized FluidFM nozzle/printing tip.

Print in liquid and in air. From nl to fl.
Highly reproducible.

Material can be deposited both in liquid and air environment.

When printing in air, the material transfer to a surface is mainly governed by pressure and capillary forces, while in liquid pressure and diffusion are key factors.

FluidFM can deposit volumes anywhere from sub fl to nL, depending of probe type and printing parameters.

The video shows an example of ~1 nL and ~50 fL droplet printing of protein solution on a functionalized surface in air. 

Also next to living cells

Developed to work in physiological conditions and with transparent samples. Surfaces can be patterned in vitro or substances can be delivered onto cells.

Ready to print in 5 minutes.

The preparation before an experiment just requires 5 minutes.

  1. Fill the reservoir of the chosen FluidFM probe

  2. Place samples and probe in the FluidFM Bio Series instrument

  3. Fill the microchannel

  4. Go to sample, load pattern

  5. Print 

Selected Publications

See more

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          FluidFM nanoprinting

          • Get to know FluidFM as a tool for nanoprinting

          • Understand how FluidFM nanoprinting works and how it empowers your experiments 

          • Learn which applications can benefit from FluidFM nanoprinting

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